Article
Paradoxes in carcinogenesis: new opportunities for research directions.
BMC cancer - 6 Aug 2007
Baker Stuart G, Kramer Barnett S
Abstract excerpt
BACKGROUND: The prevailing paradigm in cancer research is the somatic mutation theory that posits that cancer begins with a single mutation in a somatic cell followed by successive mutations. Much cancer research involves refining the somatic mutation theory with an ever increasing catalog of genetic changes. The problem is that such research may miss paradoxical aspects of carcinogenesis for which there is no...
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