Article
Cancers beget mutations versus mutations beget cancers.
Cancer research - 15 Oct 1994
Prehn R T
Abstract excerpt
Despite the plethora of "oncogenes" and "tumor suppressor genes," the hypothesis that cancer is usually the result of genomic mutations may be wrong. We should at least examine the alternative hypothesis, for which there is considerable evidence, that mutations do not commonly beget cancer, but r...
Topics
- Animals
- Carcinogens
- Cocarcinogenesis
- Gene Expression Regulation, Neoplastic
- Genome
- Humans
- Mutation
- Neoplasm Regression, Spontaneous
- Neoplasms
- Papilloma
- Phenotype
- Skin Neoplasms