Article
Is Cancer Reversible? Rethinking Carcinogenesis Models-A New Epistemological Tool.
Biomolecules - 24 Apr 2023
Pensotti Andrea, Bertolaso Marta, Bizzarri Mariano
Abstract excerpt
A growing number of studies shows that it is possible to induce a phenotypic transformation of cancer cells from malignant to benign. This process is currently known as "tumor reversion". However, the concept of reversibility hardly fits the current cancer models, according to which gene mutations are considered the primary cause of cancer. Indeed, if gene mutations are causative carcinogenic factors, and if gene...
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