Article
[The cause of cancer mutations: Improvable bad life or inevitable stochastic replication errors?]
Molekuliarnaia biologiia - 1 Jan 2000
Alekseenko I V, Kuzmich A I, Pleshkan V V, Tyulkina D V, Zinovyeva M V, Kostina M B, Sverdlov E D
Abstract excerpt
Despite substantial progress in understanding the mechanisms of carcinogenesis and fighting oncology diseases, cancer mortality remains rather high. Therefore, there is a striving to reduce this mortality to the level determined by endogenous biological factors. The review analyzes the mutations that lead to cell malignant transformation and describes the contribution that self-renewal of adult tissues makes to...
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