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Article

FGF signaling is required for brain left-right asymmetry and brain midline formation.

Developmental biology - 1 Feb 2014

Neugebauer Judith M, Yost H Joseph

Abstract excerpt

Early disruption of FGF signaling alters left-right (LR) asymmetry throughout the embryo. Here we uncover a role for FGF signaling that specifically disrupts brain asymmetry, independent of normal lateral plate mesoderm (LPM) asymmetry. When FGF signaling is inhibited during mid-somitogenesis, asymmetrically expressed LPM markers southpaw and lefty2 are not affected. However, asymmetrically expressed brain...

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Identifiers

PMID: 24333178
DOI: 10.1016/j.ydbio.2013.11.020
PMCID: PMC3970204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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