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Article

High incidence of CTLA-4 AA (CT60) polymorphism in renal cell cancer.

Human immunology - 1 Aug 2007

Cozar Jose M, Romero Jose M, Aptsiauri Natalia, Vazquez Fernando, Vilchez Jose R, Tallada Miguel, Garrido Federico, Ruiz-Cabello Francisco

Abstract excerpt

Polymorphism in genes encoding T-cell regulatory proteins and cytokines may influence inflammation and cancer development via regulation of antitumor immune response. In the current study we analyzed genotypic frequencies of cytotoxic T-lymphocyte antigen-4 (CTLA-4)/CT60, CTLA-4/A49G, interleukin (IL)-4, and IL-10 polymorphisms in 117 renal cell carcinoma patients, 96 patients with colorectal cancer, and 196...

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Source

Identifiers

PMID: 17678726
DOI: 10.1016/j.humimm.2007.05.002

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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