Article
Impact of interleukin-18 polymorphisms-607 and -137 on clinical characteristics of renal cell carcinoma patients.
Human immunology - 1 Mar 2010
Sáenz-López Pablo, Carretero Rafael, Vazquez Fernando, Martin Javier, Sánchez Elena, Tallada Miguel, Garrido Federico, Cózar José Manuel, Ruiz-Cabello Francisco
Abstract excerpt
Current evidence suggests that chronic inflammation is associated with tumor development and progression. Interleukin-18 (IL-18) plays a central role in inflammation and the immune response, contributing to the pathogenesis and pathophysiology of infectious and inflammatory diseases. The objective of this study was to determine whether the presence of IL-18 polymorphisms -137 G/C (rs187238) and -607 A/C...
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