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Polymorphisms in the CTLA-4 gene and rheumatoid arthritis susceptibility: a meta-analysis.

Journal of clinical immunology - 1 Jun 2012

Li Xiaobo, Zhang Cong, Zhang Jie, Zhang Yonggang, Wu Zhangjun, Yang Lian, Xiang Zhangpeng, Qi Zhanzhong, Zhang Xin, Xiao Xingqiong

Abstract excerpt

INTRODUCTION: The +49A/G polymorphism and CT60 polymorphism in the CTLA-4 gene have been extensively examined for the association with rheumatoid arthritis (RA); however, results of different studies have been inconclusive. The aim of this study is to comprehensively evaluate the genetic risks of +49A/G and CT60 polymorphisms in the CTLA-4 gene for RA. METHODS: A meta-analysis was carried out to analyze the...

Topics

Arthritis, Rheumatoid
CTLA-4 Antigen
Genetic Predisposition to Disease
Genotype
Humans
Polymorphism, Genetic

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22354566
DOI: 10.1007/s10875-012-9650-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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