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Article

Association of IL-4 -590 T>C polymorphism and risk of renal cell carcinoma in a Chinese population.

International journal of immunogenetics - 1 Dec 2010

Zhu J, Ju X, Yan F, Qin C, Wang M, Ding Q, Zhang Z, Yin C

Abstract excerpt

Interleukin 4 (IL-4) is a typical pleiotropic T helper 2 (Th2) cytokine. This cytokine is a critical mediator of the Th1/Th2 balance and apoptosis potential and involved in the process of inflammation-mediated carcinogenesis in human organs, including renal cell carcinoma (RCC). The effects of functional promoter polymorphism of the IL-4 gene on risk of RCC in Chinese are still unknown. In this study, we...

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PMID: 20618516
DOI: 10.1111/j.1744-313X.2010.00948.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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