Article
Association of IL-4 -590 T>C polymorphism and risk of renal cell carcinoma in a Chinese population.
International journal of immunogenetics - 1 Dec 2010
Zhu J, Ju X, Yan F, Qin C, Wang M, Ding Q, Zhang Z, Yin C
Abstract excerpt
Interleukin 4 (IL-4) is a typical pleiotropic T helper 2 (Th2) cytokine. This cytokine is a critical mediator of the Th1/Th2 balance and apoptosis potential and involved in the process of inflammation-mediated carcinogenesis in human organs, including renal cell carcinoma (RCC). The effects of fu...
Topics
- Adult
- Aged
- Asian People
- Carcinoma, Renal Cell
- Case-Control Studies
- China
- Female
- Gene Expression
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-4
- Kidney Neoplasms
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic