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Article

The -590C/T polymorphism in the IL-4 gene and the risk of cancer: a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2013

Zhang Jie, Xie Danli, Zhou Huaibin, Fan Runping, Zhang Longyi, Li Cixiu, Jin Sheng, Meng Qinghe, Lu Jianxin

Abstract excerpt

Interleukin-4 (IL-4) plays an important role in the pathogenesis of cancer. The -590C/T polymorphism in the IL-4 gene has been implicated in susceptibility to cancer, but the results have been inconclusive. The aim of this study was to analyze the association between this polymorphism with the risk of cancer by meta-analysis. PubMed, Embase, CNKI, and Wanfang databases were searched for all publications...

Topics

Asian People
Case-Control Studies
Colorectal Neoplasms
Genetic Predisposition to Disease
Genotype
Humans
Interleukin-4
Neoplasms
Polymorphism, Single Nucleotide
Risk

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Stomach Neoplasms

White People

Source

Identifiers

PMID: 23576103
DOI: 10.1007/s13277-013-0767-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23576103-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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