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Article

Normal regulation of Rbf1/E2f1 target genes in Drosophila type 1 protein phosphatase mutants.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Sept 2007

Swanhart Lisa M, Sanders Akeisha N, Duronio Robert J

Abstract excerpt

G1 Cyclin/Cdk complexes phosphorylate and inactivate the pRb tumor suppressor by preventing its ability to bind and repress E2F transcription factors. Current molecular and biochemical evidence suggests that type 1 protein phosphatases (PP1) dephosphorylate and thereby activate pRb, but the funct...

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Identifiers

PMID: 17676643
DOI: 10.1002/dvdy.21265

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17676643-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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