Decreased expression of Krüppel-like factors in memory B cells induces the rapid response typical of secondary antibody responses

Abstract excerpt

Secondary antibody responses are characterized by the rapid kinetics of the responding cells, including the production of larger amounts of serum Ig compared with the primary response. Memory B cells, which are responsible for this phenomenon, undergo greater proliferation and differentiation into Ig-secreting plasma cells than naïve B cells. We have found that memory cells rapidly enter cell division,...

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