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Article

Role of Krüppel-like factors in leukocyte development, function, and disease

9 Jul 2010

Abstract excerpt

The Krüppel-like transcription factor (KLF) family participates in diverse aspects of cellular growth, development, differentiation, and activation. Recently, several groups have identified new connections between the function of these factors and leukocyte responses in health and disease. Gene targeting of individual KLFs in mice has uncovered novel and unexpected physiologic roles among myeloid and lymphocyte...

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Identifiers

PMID: 20616217
DOI: 10.1182/blood-2010-05-285353

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