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Article

The Dcr2p phosphatase destabilizes Sic1p in Saccharomyces cerevisiae.

Biochemical and biophysical research communications - 28 Sept 2007

Pathak Ritu, Blank Heidi M, Guo Jinbai, Ellis Sarah, Polymenis Michael

Abstract excerpt

Initiation of cell division is controlled by an irreversible switch. In Saccharomyces cerevisiae degradation of the Sic1p protein, an inhibitor of mitotic cyclin/cyclin-dependent kinase complexes, takes place before initiation of DNA replication, at a point called START. Sic1p is phosphorylated b...

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Identifiers

PMID: 17673172
DOI: 10.1016/j.bbrc.2007.07.092
PMCID: PMC2031908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17673172-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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