Article
No association between interleukin-18 gene polymorphisms and haplotypes in Dutch sarcoidosis patients.
Tissue antigens - 1 Jun 2004
Janssen R, Grutters J C, Ruven H J T, Zanen P, Sato H, Welsh K I, du Bois R M, van den Bosch J M M
Abstract excerpt
Previously, an association between susceptibility to sarcoidosis and a polymorphism in the interleukin (IL-18) gene (IL-18 -607A/C) has been reported in Japanese. The aim of the present study was to validate this association in a clinically well-characterized population of Dutch Caucasians. Three other polymorphisms at positions -656, -137, and 1248 were included in order to extend the mapping of the IL-18 gene...
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