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Article

Roles of functional polymorphisms in the interleukin-18 gene promoter in sarcoidosis.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG - 1 Jun 2005

Zhou Yanqiu, Yamaguchi Etsuro, Hizawa Nobuyuki, Nishimura Masaharu

Abstract excerpt

BACKGROUND AND AIM OF THE WORK: Interleukin (IL)-18 plays important roles in sarcoidosis by inducing interferon-gamma in synergy with IL-12. Results of case-control studies on the association between sarcoidosis and single nucleotide polymorphisms (SNPs) in the IL-18 gene promoter are conflicting. We reexamined the association and evaluated the clinical significance of the SNPs in sarcoidosis. METHODS: Genotyping...

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PMID: 16053025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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