Article
Cytokine and cytokine receptor gene polymorphisms and their functionality.
Cytokine & growth factor reviews - 1 Feb 2009
Smith Andrew J P, Humphries Steve E
Abstract excerpt
Cytokines, signaling proteins produced by a variety of cell types, are essential for the development and functioning of both innate and adaptive immune response. Cytokine gene expression is tightly regulated, and aberrant expression from environmental and genetic polymorphism has been implicated in a range of diseases, susceptibility to infections, and responses to treatment. This review concentrates on the...
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