Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of response to exogenous interferon-α in the liver of chimpanzees chronically infected with hepatitis C virus

1 Aug 2007

Abstract excerpt

UNLABELLED: The mechanism of the interferon-alpha (IFNalpha)-induced antiviral response is not completely understood. We recently examined the transcriptional response to IFNalpha in uninfected chimpanzees. The transcriptional response to IFNalpha in the liver and peripheral blood mononuclear cells (PBMCs) was rapidly induced but was also rapidly down-regulated, with most interferon-alpha-stimulated genes (ISGs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Hepatitis C virus research
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17668868
DOI: 10.1002/hep.21776

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of response to exogenous interferon-α in the liver of chimpanzees chronically infected with hepatitis C virusPMID 17668868Read ↗

Genomic response to interferon-α in chimpanzees: Implications of rapid downregulation for hepatitis C kineticsSemantic proximity Read ↗

Genomic analysis of the host response to hepatitis C virus infectionSemantic proximity Read ↗

Intrahepatic Gene Expression during Chronic Hepatitis C Virus Infection in ChimpanzeesSemantic proximity Read ↗

IL-29 is the dominant type III interferon produced by hepatocytes during acute hepatitis C virus infection.Semantic proximity Read ↗

Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment responseSemantic proximity Read ↗

Genomic analysis of the host response to hepatitis B virus infectionSemantic proximity Read ↗

Innate immune tolerance and the role of kupffer cells in differential responses to interferon therapy among patients with HCV genotype 1 infection.Semantic proximity Read ↗

Differential Transcriptional Responses to Interferon-α and Interferon-γ in Primary Human HepatocytesSemantic proximity Read ↗

Interferon type I gene expression in chronic hepatitis CSemantic proximity Read ↗

Enhanced Expression of Interferon-Regulated Genes in the Liver of Patients with Chronic Hepatitis C Virus Infection: Detection by Suppression-Subtractive HybridizationSemantic proximity Read ↗

Interferon signaling and treatment outcome in chronic hepatitis C.Semantic proximity Read ↗

Pathogenesis of Hepatitis E Virus and Hepatitis C Virus in Chimpanzees: Similarities and DifferencesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.