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Article

IL-29 is the dominant type III interferon produced by hepatocytes during acute hepatitis C virus infection.

Hepatology (Baltimore, Md.) - 1 Dec 2012

Park Heiyoung, Serti Elisavet, Eke Onyinyechi, Muchmore Brian, Prokunina-Olsson Ludmila, Capone Stefania, Folgori Antonella, Rehermann Barbara

Abstract excerpt

UNLABELLED: Early, vigorous intrahepatic induction of interferon (IFN)-stimulated gene (ISG) induction is a feature of hepatitis C virus (HCV) infection, even though HCV inhibits the induction of type I IFNs in vitro. To identify the cytokines and cells that drive ISG induction and mediate antiviral activity during acute HCV infection, type I and III IFN responses were studied in (1) serial liver biopsies and...

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Identifiers

PMID: 22706965
DOI: 10.1002/hep.25897
PMCID: PMC3581145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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