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Article

Interferon signaling and treatment outcome in chronic hepatitis C.

Proceedings of the National Academy of Sciences of the United States of America - 13 May 2008

Sarasin-Filipowicz Magdalena, Oakeley Edward J, Duong Francois H T, Christen Verena, Terracciano Luigi, Filipowicz Witold, Heim Markus H

Abstract excerpt

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide. The current standard therapy for chronic hepatitis C (CHC) consists of a combination of pegylated IFN alpha (pegIFNalpha) and ribavirin. It achieves a sustained viral clearance in only 50-60% of patients. To le...

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PMID: 18467494
DOI: 10.1073/pnas.0707882105
PMCID: PMC2383932

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STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18467494-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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