Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic analysis of the host response to hepatitis C virus infection

19 Nov 2002

Abstract excerpt

We have examined the progression of hepatitis C virus (HCV) infections by gene expression analysis of liver biopsies in acutely infected chimpanzees that developed persistent infection, transient viral clearance, or sustained clearance. Both common responses and outcome-specific changes in expression were observed. All chimpanzees showed gene expression patterns consistent with an IFN-alpha response that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis C virus research
Share to Liver Disease Diagnosis and Treatment
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12441396
DOI: 10.1073/pnas.202608199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic analysis of the host response to hepatitis C virus infectionPMID 12441396Read ↗

Intrahepatic Gene Expression during Chronic Hepatitis C Virus Infection in ChimpanzeesSemantic proximity Read ↗

Genomic response to interferon-α in chimpanzees: Implications of rapid downregulation for hepatitis C kineticsSemantic proximity Read ↗

Genomic analysis of the host response to hepatitis B virus infectionSemantic proximity Read ↗

Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virusSemantic proximity Read ↗

Pathogenesis of Hepatitis E Virus and Hepatitis C Virus in Chimpanzees: Similarities and DifferencesSemantic proximity Read ↗

Lack of response to exogenous interferon-α in the liver of chimpanzees chronically infected with hepatitis C virusSemantic proximity Read ↗

Liver Gene Expression Profiles Correlate with Virus Infection and Response to Interferon Therapy in Chronic Hepatitis B PatientsSemantic proximity Read ↗

Host response transcriptomic analysis of Crimean-Congo hemorrhagic fever pathogenesis in the cynomolgus macaque modelSemantic proximity Read ↗

Transcriptome sequencing, microarray, and proteomic analyses reveal cellular and metabolic impact of hepatitis C virus infection in vitro†‡§Semantic proximity Read ↗

Early Transcriptional Divergence Marks Virus-Specific Primary Human CD8+ T Cells in Chronic versus Acute Infection.Semantic proximity Read ↗

Gene Expression Profiling To Predict and Assess the Consequences of Therapy-Induced Virus Eradication in Chronic Hepatitis C Virus InfectionSemantic proximity Read ↗

Transcriptome analysis in rhesus macaques infected with hepatitis E virus genotype 1/3 infections and genotype 1 re-infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.