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Article

Differential Transcriptional Responses to Interferon-α and Interferon-γ in Primary Human Hepatocytes

28 Dec 2009

Abstract excerpt

Interferon (IFN) plays a central role in the innate and adaptive antiviral immune responses. While IFN-alpha is currently approved for treating chronic hepatitis B and hepatitis C, in limited studies, IFN-gamma has not been shown to be effective for chronic hepatitis B or C. To identify the potential mechanism underlying the differential antiviral effects of IFN-alpha and IFN-gamma, we used cDNA microarray to...

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PMID: 20038212
DOI: 10.1089/jir.2009.0082

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