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Article

Altered DNA binding by the human Rad51-R150Q mutant found in breast cancer patients.

Biological & pharmaceutical bulletin - 1 Aug 2007

Ishida Takako, Takizawa Yoshimasa, Sakane Isao, Kurumizaka Hitoshi

Abstract excerpt

The human Rad51 protein (HsRad51) catalyzes homologous pairing and strand exchange between single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) during recombinational repair of double-stranded DNA breaks. An HsRad51 mutation that results in the substitution of Gln for Arg150 (R150Q) was found in bilateral breast cancer patients; however, the consequences of this R150Q mutation have not been elucidated. To...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17666788
DOI: 10.1248/bpb.30.1374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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