Article
The Lys313 residue of the human Rad51 protein negatively regulates the strand-exchange activity.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jan 2008
Ishida Takako, Takizawa Yoshimasa, Sakane Isao, Kurumizaka Hitoshi
Abstract excerpt
The Rad51 protein, which catalyzes homologous-pairing and strand-exchange reactions, is an essential enzyme for homologous recombinational repair (HRR) and meiotic homologous recombination in eukaryotes. In humans, the conventional Rad51 (HsRad51) protein has a Lys residue at position 313; howeve...
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