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Article

Heterology tolerance and recognition of mismatched base pairs by human Rad51 protein.

DNA repair - 3 Apr 2011

Tsai Yu-Cheng, Wang Yuzhen, Urena Damian E, Kumar Sandip, Chen Junghuei

Abstract excerpt

Human Rad51 (hRad51) promoted homology recognition and subsequent strand exchange are the key steps in human homologous recombination mediated repair of DNA double-strand breaks. However, it is still not clear how hRad51 deals with sequence heterology between the two homologous chromosomes in eukaryotic cells, which would lead to mismatched base pairs after strand exchange. Excessive tolerance of sequence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21239234
DOI: 10.1016/j.dnarep.2010.12.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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