Article
[Diagnosis of colorectal cancer from DNA level].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jan 1991
Shirasawa S, Yanagawa Y, Sasazuki T
Abstract excerpt
The inherited cancer-inducing disease familial polyposis coli (FPC) provides an excellent model not only for studying tumor progression in colorectal cancer but also for elucidating molecular mechanisms in general oncogenesis. This paper reviewed recent remarkable progresses of molecular mechanisms in colorectal tumorigenesis. This is concerned with the various kinds of genetic alterations that accumulate in the...
Topics
- Adenoma
- Adenomatous Polyposis Coli
- Colorectal Neoplasms
- DNA, Neoplasm
- Gene Expression Regulation, Neoplastic
- Genes, DCC
- Genes, p53
- Genes, ras
- Heterozygote
- Humans
- Mutation
