Article
Platelet genomics and the risk of atherothrombosis.
Journal of thrombosis and haemostasis : JTH - 1 Jul 2007
Ouwehand W H
Abstract excerpt
Platelets play a pivotal role in atherothrombosis after coronary artery plaque rupture. The extent of response of platelets to such an event varies between individuals. This variation is for a large extent genetically controlled. A comprehensive study of sequence variation that modifies the platelet response to agonists is, however, lacking. We set out to discover the regulatory nodes of platelet function by an...
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