Article
Mhc-DRB genes of the pigtail macaque (Macaca nemestrina): implications for the evolution of human DRB genes.
Molecular biology and evolution - 1 Sept 1991
Zhu Z F, Vincek V, Figueroa F, Schönbach C, Klein J
Abstract excerpt
The DRB family of human class II major histocompatibility complex (Mhc) loci is unusual in that individuals differ in the number and combination of genes (haplotypes) they carry. Indications are that both the allelic and haplotype polymorphisms of the DRB loci predate speciation. Searching for th...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Evolution
- Cell Line
- DNA Probes
- Gene Library
- Genes, MHC Class II
- HLA-B Antigens
- HLA-DR Antigens
- Hominidae
- Humans
- Macaca nemestrina
- Major Histocompatibility Complex
- Models, Genetic
- Molecular Sequence Data
- Sequence Homology, Nucleic Acid