Article
Identification of novel MHC class I sequences in pig-tailed macaques by amplicon pyrosequencing and full-length cDNA cloning and sequencing.
Immunogenetics - 1 Oct 2009
O'Leary Claire E, Wiseman Roger W, Karl Julie A, Bimber Benjamin N, Lank Simon M, Tuscher Jennifer J, O'Connor David H
Abstract excerpt
Pig-tailed macaques (Macaca nemestrina) provide important animal models in biomedical research, but utility of this species for HIV and other disease pathogenesis research is limited by incomplete knowledge of major histocompatibility complex (MHC) class I genetics. Here, we describe comprehensive MHC class I genotyping of 24 pig-tailed macaques, using pyrosequencing to evaluate a 367- bp complementary DNA...
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