Article
Allelic diversification at the class II DQB locus of the mammalian major histocompatibility complex.
Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1990
Gyllensten U B, Lashkari D, Erlich H A
Abstract excerpt
The allelic diversity at HLA class II loci either arose after the divergence of hominoid lineages or, alternatively, the polymorphism was present before speciation and has been maintained by selection. Here, we report the use of oligonucleotide primers to amplify, by the polymerase chain reaction...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Genetic Variation
- Gorilla gorilla
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Hominidae
- Humans
- Major Histocompatibility Complex
- Mammals
- Molecular Sequence Data
- Pan troglodytes
- Phylogeny
- Polymerase Chain Reaction
- Primates
- Sequence Homology, Nucleic Acid