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Article

Survey of major histocompatibility complex class II diversity in pig-tailed macaques.

Immunogenetics - 1 Nov 2014

Karl Julie A, Heimbruch Katelyn E, Vriezen Claire E, Mironczuk Cassandra J, Dudley Dawn M, Wiseman Roger W, O'Connor David H

Abstract excerpt

Pig-tailed macaques (Macaca nemestrina) serve as important models for human infectious disease research. Major histocompatibility complex (MHC) class II molecules are important to this research since they present peptides to CD4+ T cells. Despite the importance of characterizing the MHC-II alleles expressed in model species like pig-tailed macaques, to date, less than 150 MHC-II alleles have been named for the...

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Identifiers

PMID: 25129472
DOI: 10.1007/s00251-014-0797-y
PMCID: PMC4198495

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