Article
Characterization of pig-tailed macaque classical MHC class I genes: implications for MHC evolution and antigen presentation in macaques.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 2003
Lafont Bernard A P, Buckler-White Alicia, Plishka Ron, Buckler Charles, Martin Malcolm A
Abstract excerpt
MHC-dependent CD8(+) T cell responses have been associated with control of viral replication and slower disease progression during lentiviral infections. Pig-tailed macaques (Macaca nemestrina) and rhesus monkeys (Macaca mulatta), two nonhuman primate species commonly used to model HIV infection, can exhibit distinct clinical courses after infection with different primate lentiviruses. As an initial step in...
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