Article
Screening and confirmatory testing of MHC class I alleles in pig-tailed macaques.
Immunogenetics - 1 Aug 2011
Fernandez Caroline S, Reece Jeanette C, Saepuloh Uus, De Rose Robert, Ishkandriati Diah, O'Connor David H, Wiseman Roger W, Kent Stephen J
Abstract excerpt
Pig-tailed macaques (Macaca nemestrina) are a commonly studied primate model of human AIDS. The Mane-A1*084:01 MHC class I allele (previously named Mane-A*10) is important for the control of SIV infection by CD8+ T cells in this model. Validated methods to detect this allele in large numbers of macaques are lacking. We studied this MHC allele using sequence-specific PCRs in 217 pig-tailed macaques and identified...
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