Article
DQA-DQB linkage in Old World monkeys.
Tissue antigens - 1 Apr 1998
Gaur L K, Pandarpurkar M, Anderson J
Abstract excerpt
The MHC DQ region in nonhuman primates, as in humans, consists of alpha and beta chains that are polymorphic with strong linkage disequilibrium between certain DQA-DQB alleles. Not only are contemporary HLA class II allelic variants present in evolutionarily distant species, but we demonstrate th...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Female
- Genetic Linkage
- Histocompatibility Antigens Class II
- Humans
- Macaca nemestrina
- Male
- Molecular Sequence Data
- Mutagenesis
- Papio
- Pedigree
- Sequence Homology, Amino Acid
