Article
DQA-DQB linkage in Old World monkeys.
Tissue antigens - 1 Apr 1998
Gaur L K, Pandarpurkar M, Anderson J
Abstract excerpt
The MHC DQ region in nonhuman primates, as in humans, consists of alpha and beta chains that are polymorphic with strong linkage disequilibrium between certain DQA-DQB alleles. Not only are contemporary HLA class II allelic variants present in evolutionarily distant species, but we demonstrate that linkages between loci also bear ancient roots. In unrelated baboons (Papio cynocephalus anubis) and family...
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