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Article

Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma.

World journal of gastroenterology - 7 Aug 2007

Mukai Shinichi, Hiyama Toru, Tanaka Shinji, Yoshihara Masaharu, Arihiro Koji, Chayama Kazuaki

Abstract excerpt

AIM: To examine Kruppel-like factor 6 (KLF6) mutations in nonpolypoid-type tumors and alterations of K-ras, p53, and B-raf in relation between mutation and morphologic type, particularly nonpolypoid-type colorectal carcinomas. METHODS: Fifty-five early nonpolypoid colorectal carcinomas were analyzed. Loss of heterozygosity (LOH) of KLF6 and p53 was determined by microsatellite assay. Mutations of KLF6, K-ras, and...

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Source

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Identifiers

PMID: 17663506
DOI: 10.3748/wjg.v13.i29.3932
PMCID: PMC4171164

Genes

KLF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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