Article
Genetic and epigenetic alterations of the KLF6 gene in hepatocellular carcinoma.
Journal of gastroenterology and hepatology - 1 Aug 2006
Song Jaehwi, Kim Chang Jae, Cho Yong Gu, Kim Su Young, Nam Suk Woo, Lee Sug Hyung, Yoo Nam Jin, Lee Jung Young, Park Won Sang
Abstract excerpt
BACKGROUND AND AIM: Kruppel-like factor 6 (KLF6) is a zinc finger tumor suppressor gene that is frequently mutated in several human cancers and is broadly involved in differentiation and development, growth-related signal transduction, cell proliferation, apoptosis, and angiogenesis. The aim of this study was to elucidate the potential etiological role of KLF6 in the development of hepatocellular carcinoma (HCC)...
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