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Article

Intracellular proton conductance of the hepatitis C virus p7 protein and its contribution to infectious virus production.

PLoS pathogens - 2 Sept 2010

Wozniak Ann L, Griffin Stephen, Rowlands David, Harris Mark, Yi MinKyung, Lemon Stanley M, Weinman Steven A

Abstract excerpt

The hepatitis C virus (HCV) p7 protein is critical for virus production and an attractive antiviral target. p7 is an ion channel when reconstituted in artificial lipid bilayers, but channel function has not been demonstrated in vivo and it is unknown whether p7 channel activity plays a critical role in virus production. To evaluate the contribution of p7 to organelle pH regulation and virus production, we...

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Source

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Identifiers

PMID: 20824094
DOI: 10.1371/journal.ppat.1001087
PMCID: PMC2932723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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