Article
Association of IL-15 polymorphisms with bone mineral density in postmenopausal Korean women.
Calcified tissue international - 1 Nov 2009
Koh Jung-Min, Oh Bermseok, Ha Mi-Hyun, Cho Kyu-Woan, Lee Jong-Young, Park Byung Lae, Shin Hyoung Doo, Bae Myung-Ae, Kim Hyun-Ju, Hong Jung Min, Kim Tae-Ho, Shin Hong-In, Lee Seung Hun, Kim Ghi Su, Kim Shin-Yoon, Park Eui Kyun
Abstract excerpt
Interleukin-15 (IL-15) has been suggested to participate in bone metabolism by stimulating osteoclast differentiation and mediating inflammatory bone loss. This study investigated the effect of IL-15 gene polymorphisms on the bone mineral density (BMD) and bone fracture rates of postmenopausal women. Sequencing of the IL-15 gene in 24 Koreans revealed 16 single-nucleotide polymorphisms (SNPs), of which five were...
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