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Article

Evidence for involvement of BH3-only proapoptotic members in adenovirus-induced apoptosis.

Journal of virology - 1 Oct 2007

Subramanian T, Vijayalingam S, Lomonosova Elena, Zhao Ling-jun, Chinnadurai G

Abstract excerpt

Mammalian cells infected with human adenoviruses (Ads) undergo an apoptotic response as a result of expression of the viral E1A proteins, and this process is suppressed by the viral E1B-19K protein. The intermediary steps in the Ad-induced apoptosis pathway are not fully resolved. The apical step in the canonical mammalian apoptosis pathway involves functional activation of one or more of the BH3-only BCL-2...

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Source

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Identifiers

PMID: 17652400
DOI: 10.1128/JVI.00808-07
PMCID: PMC2045492

Genes

BIK
BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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