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Article

Characterization of the anti-apoptotic mechanism of Bcl-B.

The Biochemical journal - 15 Nov 2003

Zhai Dayong, Ke Ning, Zhang Haichao, Ladror Uri, Joseph Mary, Eichinger Andreas, Godzik Adam, Ng Shi-Chung, Reed John C

Abstract excerpt

Bcl-B protein is an anti-apoptotic member of the Bcl-2 family protein that contains all the four BH (Bcl-2 homology) domains (BH1, BH2, BH3 and BH4) and a predicted C-terminal transmembrane domain. Our previous results showed that Bcl-B binds Bax and suppresses apoptosis induced by over-expression of Bax; however, Bcl-B does not bind or suppress Bak. To explore the molecular basis for the differential binding and...

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Identifiers

PMID: 12921534
DOI: 10.1042/BJ20030374
PMCID: PMC1223753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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