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Article

Bid Protein: A Participant in the Apoptotic Network with Roles in Viral Infections

7 Mar 2025

Abstract excerpt

The BH3-interacting domain death agonist (Bid), a proapoptotic signaling molecule of the B-cell lymphoma 2 (Bcl-2) family, is a key regulator of mitochondrial outer membrane (MOM) permeability. Uniquely positioned at the intersection of extrinsic and intrinsic apoptosis pathways, Bid links death receptor signaling to the mitochondria-dependent cascade and can also be activated by endoplasmic reticulum (ER)...

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PMID: 40141030
DOI: 10.3390/ijms26062385

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