Article
Innate immunogenetics: a tool for exploring new frontiers of host defence.
The Lancet. Infectious diseases - 1 Aug 2007
Bochud Pierre-Yves, Bochud Murielle, Telenti Amalio, Calandra Thierry
Abstract excerpt
The discovery of innate immune genes, such as those encoding Toll-like receptors (TLRs), nucleotide-binding oligomerisation domain-like receptors (NLRs), and related signal-transducing molecules, has led to a substantial improvement of our understanding of innate immunity. Recent immunogenetic studies have associated polymorphisms of the genes encoding TLRs, NLRs, and key signal-transducing molecules, such as...
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