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Article

Host genetics: fine-tuning innate signaling.

Current biology : CB - 3 Jul 2007

Fellay Jacques, Goldstein David B

Abstract excerpt

A polymorphism modulating innate immunity signal transduction has recently been shown to influence human susceptibility to many different infections, providing one more indication of the potential of host genetics to reveal physiological pathways and mechanisms that influence resistance to infectious diseases.

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Share to Genetic Predisposition to Disease
Share to Immunity, Innate
Share to Membrane Glycoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Receptors, Interleukin-1

Share to Selection, Genetic

Share to Signal Transduction

Source

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Identifiers

PMID: 17610834
DOI: 10.1016/j.cub.2007.04.052
PMCID: PMC2584967

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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