Article
Integrated computational and experimental analysis of the neuroendocrine transcriptome in genetic hypertension identifies novel control points for the cardiometabolic syndrome.
Circulation. Cardiovascular genetics - 1 Aug 2012
Friese Ryan S, Ye Chun, Nievergelt Caroline M, Schork Andrew J, Mahapatra Nitish R, Rao Fangwen, Napolitan Philip S, Waalen Jill, Ehret Georg B, Munroe Patricia B, Schmid-Schönbein Geert W, Eskin Eleazar, O'Connor Daniel T
Abstract excerpt
BACKGROUND: Essential hypertension, a common complex disease, displays substantial genetic influence. Contemporary methods to dissect the genetic basis of complex diseases such as the genomewide association study are powerful, yet a large gap exists between the fraction of population trait varian...
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