Article
Is There a Role for Genomics in the Management of Hypertension?
International journal of molecular sciences - 26 May 2017
Burrello Jacopo, Monticone Silvia, Buffolo Fabrizio, Tetti Martina, Veglio Franco, Williams Tracy A, Mulatero Paolo
Abstract excerpt
Hypertension (HTN) affects about 1 billion people worldwide and the lack of a single identifiable cause complicates its treatment. Blood pressure (BP) levels are influenced by environmental factors, but there is a strong genetic component. Linkage analysis has identified several genes involved in Mendelian forms of HTN and the associated pathophysiological mechanisms have been unravelled, leading to targeted...
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