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Article

Genomics of hypertension: the road to precision medicine.

Nature reviews. Cardiology - 1 Apr 2021

Padmanabhan Sandosh, Dominiczak Anna F

Abstract excerpt

The known genetic architecture of blood pressure now comprises >30 genes, with rare variants resulting in monogenic forms of hypertension or hypotension and >1,477 common single-nucleotide polymorphisms (SNPs) being associated with the blood pressure phenotype. Monogenic blood pressure syndromes predominantly involve the renin-angiotensin-aldosterone system and the adrenal glucocorticoid pathway, with a smaller...

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PMID: 33219353
DOI: 10.1038/s41569-020-00466-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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