Article
Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.
Nature - 20 May 2010
Lourido Sebastian, Shuman Joel, Zhang Chao, Shokat Kevan M, Hui Raymond, Sibley L David
Abstract excerpt
Calcium-regulated exocytosis is a ubiquitous process in eukaryotes, whereby secretory vesicles fuse with the plasma membrane and release their contents in response to an intracellular calcium surge. This process regulates various cellular functions such as plasma membrane repair in plants and animals, the discharge of defensive spikes in Paramecium, and the secretion of insulin from pancreatic cells, immune...
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