Article
IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5.
Genes and immunity - 1 Sept 2007
Shin J-H, Janer M, McNeney B, Blay S, Deutsch K, Sanjeevi C B, Kockum I, Lernmark A, Graham J, Arnqvist Hans, Björck Elizabeth, Eriksson Jan, Nyström Lennarth, Ohlson Lars Olof, Scherstén Bengt, Ostman Jan, Aili M, Bååth L E, Carlsson E, Edenwall H, Forsander G, Granström B W, Gustavsson I, Hanås R, Hellenberg L, Hellgren H, Holmberg E, Hörnell H, Ivarsson Sten-A, Johansson C, Jonsell G, Kockum K, Lindblad B, Lindh A, Ludvigsson J, Myrdal U, Neiderud J, Segnestam K, Sjöblad S, Skogsberg L, Strömberg L, Ståhle U, Thalme B, Tullus K, Tuvemo T, Wallensteen M, Westphal O, Aman J
Abstract excerpt
In a large case-control study of Swedish incident type I diabetes patients and controls, 0-34 years of age, we tested the hypothesis that the GIMAP5 gene, a key genetic factor for lymphopenia in spontaneous BioBreeding rat diabetes, is associated with type I diabetes; with islet autoantibodies in incident type I diabetes patients or with age at clinical onset in incident type I diabetes patients. Initial scans of...
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