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Article

Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12.

Diabetologia - 1 Jul 2018

Achenbach Peter, Hawa Mohammed I, Krause Stephanie, Lampasona Vito, Jerram Samuel T, Williams Alistair J K, Bonifacio Ezio, Ziegler Anette G, Leslie R David

Abstract excerpt

AIMS/HYPOTHESIS: Adult-onset type 1 diabetes, in which the 65 kDa isoform of GAD (GAD65) is a major autoantigen, has a broad clinical phenotype encompassing variable need for insulin therapy. This study aimed to evaluate whether autoantibodies against N-terminally truncated GAD65 more closely defined a type 1 diabetes phenotype associated with insulin therapy. METHODS: Of 1114 participants with adult-onset...

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Identifiers

PMID: 29619531
DOI: 10.1007/s00125-018-4605-3
PMCID: PMC6445455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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