Article
The protein tyrosine phosphatase nonreceptor 22 (PTPN22) is associated with high GAD antibody titer in latent autoimmune diabetes in adults: Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study 3.
Diabetes care - 1 Mar 2008
Petrone Antonio, Suraci Concetta, Capizzi Marco, Giaccari Andrea, Bosi Emanuele, Tiberti Claudio, Cossu Efisio, Pozzilli Paolo, Falorni Alberto, Buzzetti Raffaella
Abstract excerpt
OBJECTIVE: We previously demonstrated the presence of two different populations among individuals with adult-onset autoimmune diabetes: those having either a high titer or a low titer of antibodies to GAD (GADAs). Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) has been identified as a new susceptibility gene for type 1 diabetes and other autoimmune diseases. The aim of the present study was to evaluate...
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